Main Background

HyloPReP™ – HA + LP-PRP Hybrid System for OA Repair

HyloPReP™ – HA + LP-PRP Hybrid System for OA Repair

HyloPReP™ – HA + LP-PRP Hybrid System for OA Repair

HyloPReP™ is our “first-of-its-kind” combination integrating Leukocyte Poor-PRP LP- PRP kit and Hyaluronic Acid (HA) for targeted osteoarthritis (OA) management

HyloPReP™ is our “first-of-its-kind” combination integrating Leukocyte Poor-PRP LP- PRP kit and Hyaluronic Acid (HA) for targeted osteoarthritis (OA) management

HyloPReP™ is our “first-of-its-kind” combination integrating Leukocyte Poor-PRP LP- PRP kit and Hyaluronic Acid (HA) for targeted osteoarthritis (OA) management

Download brochure
Download brochure
Download brochure
Download brochure

Synergistic Healing: HA Meets PRP

Synergistic Healing: HA Meets PRP

HyloPReP™ is a next-generation combination therapy that hydrates joints, supports cartilage healing, and improves mobility in patients with osteoarthritis of the knee. It Helps patients delay arthroplasty or overdependence on steriods.It delivers two biological benefits in one injection:

HyloPReP™ is a next-generation combination therapy that hydrates joints, supports cartilage healing, and improves mobility in patients with osteoarthritis of the knee. It Helps patients delay arthroplasty or overdependence on steriods.It delivers two biological benefits in one injection:

Hyaluronic Acid (HA)

Restores lubrication and viscoelasticity in the synovial joint.

Leukocyte-Poor PRP

Delivers concentrated growth factors minus WBCs to promote cartilage repair and reduce inflammation.

Synergistic Healing: HA Meets PRP

HyloPReP™ is a next-generation combination therapy that hydrates joints, supports cartilage healing, and improves mobility in patients with osteoarthritis of the knee. It Helps patients delay arthroplasty or overdependence on steriods.It delivers two biological benefits in one injection:

Hyaluronic Acid (HA)

Restores lubrication and viscoelasticity in the synovial joint.

Leukocyte-Poor PRP

Delivers concentrated growth factors minus WBCs to promote cartilage repair and reduce inflammation.

What makes HyloPReP™ unique?
Based On

Synergistic Lubricative Regenerative Technology joints

Effective

Lubricates & Preserves Joint System

Versatile

One-Step Holistic Approach for OA repair

Available in two versions for procedural flexibility

Available in two versions for procedural flexibility
Visual
HyloPReP™ S Kit:

HA (2 mL) + LP-PRP (4–5 mL) — 1 month shot × 2 sessions.

Visual
HyloPReP™ S Kit:

HA (2 mL) + LP-PRP (4–5 mL) — 1 month shot × 2 sessions.

Visual
HyloPReP™ L Kit

HA (6 mL) + LP-PRP (4-5 mL) Single injection, 6–12-month interval.

Visual
HyloPReP™ L Kit

HA (6 mL) + LP-PRP (4-5 mL) Single injection, 6–12-month interval.

Visual
HyloPReP™ S Kit:

HA (2 mL) + LP-PRP (4–5 mL) — 1 month shot × 2 sessions.

Visual
HyloPReP™ L Kit

HA (6 mL) + LP-PRP (4-5 mL) Single injection, 6–12-month interval.

Clinical Benefits – Backed by Science, Built for Relief

Clinical Benefits – Backed by Science, Built for Relief

Pain & Function: Clinical studies show combined HA + PRP injections outperform either alone in reducing pain and improving WOMAC & VAS scores for 6–12 months

Pain & Function: Clinical studies show combined HA + PRP injections outperform either alone in reducing pain and improving WOMAC & VAS scores for 6–12 months

Chondroprotective Action: Growth factors from LP-PRP upregulate collagen II and suppress MMPs, slowing OA progression

Chondroprotective Action: Growth factors from LP-PRP upregulate collagen II and suppress MMPs, slowing OA progression

At 6-month follow-up, the HA + PRP group demonstrated the greatest reduction in WOMAC and VAS scores, showing continuous improvement up to 6 months with no major complications

At 6-month follow-up, the HA + PRP group demonstrated the greatest reduction in WOMAC and VAS scores, showing continuous improvement up to 6 months with no major complications

A systematic review of 11 RCTs (n≈1023) confirmed that PRP + HA therapy is safe and provides superior pain relief and functional improvement compared to PRP alone, with a low adverse-event rate

A systematic review of 11 RCTs (n≈1023) confirmed that PRP + HA therapy is safe and provides superior pain relief and functional improvement compared to PRP alone, with a low adverse-event rate

What makes HyloPReP™ unique?

Based On

Synergistic Lubricative Regenerative Technology joints

Effective

Lubricates and Preserves Joint System

Versatile

One-Step Holistic Approach for OA repair

Comparative Edge - For Clinicians
Who Want Predictable Outcomes

Comparative Edge - For Clinicians
Who Want Predictable Outcomes
Feature / Benefit

HyloPReP™

Generic HA + PRP Injections

System Type

The total amount of cloud storage space allocated for your files.

Closed, sterile, ISO 13485

Open / mixed preparation

PRP Type

The speed at which you can upload and download files to and from the cloud.

LP-PRP (> 90 % WBC reduction)

Variable (often LR-PRP)

HA Quality

The largest file size you can upload in a single action.

European-grade, GMP verified

Generic

Dual Mechanism

The total amount of cloud storage space allocated for your files.

Lubrication + Regeneration

Lubrication only

Relief Duration

The speed at which you can upload and download files to and from the cloud.

6–12 months

2–4 months

Affordability

Manage access with a specified number of user accounts per plan.

Economical

Expensive

Potential Indications

  • Knee Osteoarthritis (Grade I–III)
  • Shoulder, Hip, and Ankle OA
  • Patients unfit or unwilling for surgery
  • Athletes / early OA cases seeking long-term mobility
Precision for Every Specialty
  • Knee Osteoarthritis (Grade I–III)
  • Athletes / early OA cases seeking long-term mobility
  • Patients unfit or unwilling for surgery
  • Shoulder, Hip, and Ankle OA

Answers to Common Questions

Answers to Common Questions

We’ve gathered the most frequently asked questions to help you better understand our AI services, pricing, and integration process.

We’ve gathered the most frequently asked questions to help you better understand our AI services, pricing, and integration process.

Support Avatar

Need more help?

We're here to answer any questions you may have.

Ask a Question

Support Avatar

Need more help?

We're here to answer any questions you may have.

Ask a Question

How does HyloPReP™ work to relieve OA symptoms and repair cartilage?

What’s the difference between HyloPReP™ S and L kits?

How soon do patients feel improvement?

Can HyloPReP™ be used in combination with PRP or BMAC?

How does HyloPReP™ compare in safety and cost?

How does HyloPReP™ work to relieve OA symptoms and repair cartilage?

What’s the difference between HyloPReP™ S and L kits?

How soon do patients feel improvement?

Can HyloPReP™ be used in combination with PRP or BMAC?

How does HyloPReP™ compare in safety and cost?

References

References

1. Altman R.D. et al., Cartilage (2015): “Synergistic effects of HA + PRP in knee OA pain and function.”

2. Ozturk M. et al., J Orthop Surg Res (2018): “HA + PRP injections improve pain and WOMAC scores vs HA alone.”

3. Maheu E. et al., Rheumatology Int (2019): “Meta-analysis confirms additive benefits of PRP and HA in OA.”

Bring the Future of Regenerative Medicine to Your Patients — Today.

Request

a Demo

Get Started

Cta Image
Cta Image

Bring the Future of Regenerative Medicine to Your Patients — Today.

Request

a Demo

Get Started

Bring the Future of Regenerative Medicine to Your Patients — Today.

Request

a Demo

Get Started

Cta Image
Cta Image

Explore products